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The�medication�works�by�preventing�the�two�neurotransmitters�from�being�reabsorbed�by�the�nerves. Only apply a dime size amount because anymore than which could cause irritation. As medications and a pill affect individuals differently, rather than fully discovered in studies, would it not cut back lives to boost awareness about medication risks along with the possibility of suicidal thoughts generally speaking, albeit a downer on pharmaceutical sales. Or why not a family member continues to be on an antidepressant which has been working wonderfully, and after that soon after starting it, it began losing its full effect. Bupropion, also generally known as Wellbutrin (as an anti-depressant) and Zyban (as being a smoke cessation aide) features a black box warning for suicidal tendencies and suicide completion. 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